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Chemical genomic profiling via barcode sequencing to predict compound mode of action

Chemical genomics is an unbiased, whole-cell approach to characterizing novel compounds to determine mode of action and cellular target. Our version of this technique is built upon barcoded deletion mutants of Saccharomyces cerevisiae and has been adapted to a high-throughput methodology using next-...

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Bibliografske podrobnosti
izdano v:Methods Mol Biol
Main Authors: Piotrowski, Jeff S., Simpkins, Scott W., Li, Sheena C., Deshpande, Raamesh, McIlwain, Sean, Ong, Irene, Myers, Chad L., Boone, Charlie, Andersen, Raymond J.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4497522/
https://ncbi.nlm.nih.gov/pubmed/25618354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-2269-7_23
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