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Chemical genomic profiling via barcode sequencing to predict compound mode of action

Chemical genomics is an unbiased, whole-cell approach to characterizing novel compounds to determine mode of action and cellular target. Our version of this technique is built upon barcoded deletion mutants of Saccharomyces cerevisiae and has been adapted to a high-throughput methodology using next-...

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Detalhes bibliográficos
Publicado no:Methods Mol Biol
Main Authors: Piotrowski, Jeff S., Simpkins, Scott W., Li, Sheena C., Deshpande, Raamesh, McIlwain, Sean, Ong, Irene, Myers, Chad L., Boone, Charlie, Andersen, Raymond J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4497522/
https://ncbi.nlm.nih.gov/pubmed/25618354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-2269-7_23
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