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Predicting bioprocess targets of chemical compounds through integration of chemical-genetic and genetic interactions
Chemical-genetic interactions–observed when the treatment of mutant cells with chemical compounds reveals unexpected phenotypes–contain rich functional information linking compounds to their cellular modes of action. To systematically identify these interactions, an array of mutants is challenged wi...
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| Publicado en: | PLoS Comput Biol |
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| Main Authors: | , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6226211/ https://ncbi.nlm.nih.gov/pubmed/30376562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006532 |
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