Predicting bioprocess targets of chemical compounds through integration of chemical-genetic and genetic interactions

Chemical-genetic interactions–observed when the treatment of mutant cells with chemical compounds reveals unexpected phenotypes–contain rich functional information linking compounds to their cellular modes of action. To systematically identify these interactions, an array of mutants is challenged wi...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:PLoS Comput Biol
मुख्य लेखकों: Simpkins, Scott W., Nelson, Justin, Deshpande, Raamesh, Li, Sheena C., Piotrowski, Jeff S., Wilson, Erin H., Gebre, Abraham A., Safizadeh, Hamid, Okamoto, Reika, Yoshimura, Mami, Costanzo, Michael, Yashiroda, Yoko, Ohya, Yoshikazu, Osada, Hiroyuki, Yoshida, Minoru, Boone, Charles, Myers, Chad L.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2018
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6226211/
https://ncbi.nlm.nih.gov/pubmed/30376562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006532
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