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Chemical genomic profiling via barcode sequencing to predict compound mode of action
Chemical genomics is an unbiased, whole-cell approach to characterizing novel compounds to determine mode of action and cellular target. Our version of this technique is built upon barcoded deletion mutants of Saccharomyces cerevisiae and has been adapted to a high-throughput methodology using next-...
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| Veröffentlicht in: | Methods Mol Biol |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4497522/ https://ncbi.nlm.nih.gov/pubmed/25618354 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-2269-7_23 |
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