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Unbiased Screening of Marine Sponge Extracts for Anti-Inflammatory Agents Combined with Chemical Genomics Identifies Girolline as an Inhibitor of Protein Synthesis
Toll-like receptors (TLRs) play a critical role in innate immunity, but activation of TLR signaling pathways is also associated with many harmful inflammatory diseases. Identification of novel anti-inflammatory molecules targeting TLR signaling pathways is central to the development of new treatment...
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發表在: | ACS Chem Biol |
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Main Authors: | , , , , , , , , , , , , , |
格式: | Artigo |
語言: | Inglês |
出版: |
2013
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4371607/ https://ncbi.nlm.nih.gov/pubmed/24117378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb400740c |
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