Unbiased Screening of Marine Sponge Extracts for Anti-Inflammatory Agents Combined with Chemical Genomics Identifies Girolline as an Inhibitor of Protein Synthesis

Toll-like receptors (TLRs) play a critical role in innate immunity, but activation of TLR signaling pathways is also associated with many harmful inflammatory diseases. Identification of novel anti-inflammatory molecules targeting TLR signaling pathways is central to the development of new treatment...

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Publicado no:ACS Chem Biol
Main Authors: Fung, Shan-Yu, Sofiyev, Vladimir, Schneiderman, Julia, Hirschfeld, Aaron F., Victor, Rachel E., Woods, Kate, Piotrowski, Jeff S., Deshpande, Raamesh, Li, Sheena C., de Voogd, Nicole J., Myers, Chad L., Boone, Charlie, Andersen, Raymond J., Turvey, Stuart E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4371607/
https://ncbi.nlm.nih.gov/pubmed/24117378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb400740c
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