Unbiased Screening of Marine Sponge Extracts for Anti-Inflammatory Agents Combined with Chemical Genomics Identifies Girolline as an Inhibitor of Protein Synthesis

Toll-like receptors (TLRs) play a critical role in innate immunity, but activation of TLR signaling pathways is also associated with many harmful inflammatory diseases. Identification of novel anti-inflammatory molecules targeting TLR signaling pathways is central to the development of new treatment...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:ACS Chem Biol
Prif Awduron: Fung, Shan-Yu, Sofiyev, Vladimir, Schneiderman, Julia, Hirschfeld, Aaron F., Victor, Rachel E., Woods, Kate, Piotrowski, Jeff S., Deshpande, Raamesh, Li, Sheena C., de Voogd, Nicole J., Myers, Chad L., Boone, Charlie, Andersen, Raymond J., Turvey, Stuart E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4371607/
https://ncbi.nlm.nih.gov/pubmed/24117378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb400740c
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