Cyclic nucleotide phosphodiesterase 3A–deficient mice as a model of female infertility

Since cAMP blocks meiotic maturation of mammalian and amphibian oocytes in vitro and cyclic nucleotide phosphodiesterase 3A (PDE3A) is primarily responsible for oocyte cAMP hydrolysis, we generated PDE3A-deficient mice by homologous recombination. The Pde3a(–/–) females were viable and ovulated a no...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Masciarelli, Silvia, Horner, Kathleen, Liu, Chengyu, Park, Sun Hee, Hinckley, Mary, Hockman, Steven, Nedachi, Taku, Jin, Catherine, Conti, Marco, Manganiello, Vincent
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2004
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC449752/
https://ncbi.nlm.nih.gov/pubmed/15254586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200421804
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items