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Efficient introgression of allelic variants by embryo-mediated editing of the bovine genome

The recent development of designer nucleases allows for the efficient and precise introduction of genetic change into livestock genomes. Most studies so far have focused on the introduction of random mutations in cultured cells and the use of nuclear transfer to generate animals with edited genotype...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wei, Jingwei, Wagner, Stefan, Lu, Dan, Maclean, Paul, Carlson, Daniel F., Fahrenkrug, Scott C., Laible, Götz
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496724/
https://ncbi.nlm.nih.gov/pubmed/26156133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11735
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