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Efficient nonmeiotic allele introgression in livestock using custom endonucleases
We have expanded the livestock gene editing toolbox to include transcription activator-like (TAL) effector nuclease (TALEN)- and clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9-stimulated homology-directed repair (HDR) using plasmid, rAAV, and oligonucleotide templates. Towar...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3799378/ https://ncbi.nlm.nih.gov/pubmed/24014591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1310478110 |
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