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Efficient TALEN-mediated gene knockout in livestock
Transcription activator-like effector nucleases (TALENs) are programmable nucleases that join FokI endonuclease with the modular DNA-binding domain of TALEs. Although zinc-finger nucleases enable a variety of genome modifications, their application to genetic engineering of livestock has been slowed...
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| Auteurs principaux: | , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3491456/ https://ncbi.nlm.nih.gov/pubmed/23027955 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1211446109 |
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