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Comparison of CRISPR/Cas9 and TALENs on editing an integrated EGFP gene in the genome of HEK293FT cells

BACKGROUND: Genome editors such as CRISPR/Cas9 and TALENs are at the forefront of research into methodologies for targeted modification of the mammalian genome. To date few comparative studies have been carried out to investigate the difference of genome editing characteristics between CRISPR/Cas9 a...

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Detalhes bibliográficos
Publicado no:Springerplus
Main Authors: He, Zuyong, Proudfoot, Chris, Whitelaw, C. Bruce A., Lillico, Simon G.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4916124/
https://ncbi.nlm.nih.gov/pubmed/27390654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40064-016-2536-3
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