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Comparison of CRISPR/Cas9 and TALENs on editing an integrated EGFP gene in the genome of HEK293FT cells

BACKGROUND: Genome editors such as CRISPR/Cas9 and TALENs are at the forefront of research into methodologies for targeted modification of the mammalian genome. To date few comparative studies have been carried out to investigate the difference of genome editing characteristics between CRISPR/Cas9 a...

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Bibliografski detalji
Izdano u:Springerplus
Glavni autori: He, Zuyong, Proudfoot, Chris, Whitelaw, C. Bruce A., Lillico, Simon G.
Format: Artigo
Jezik:Inglês
Izdano: Springer International Publishing 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4916124/
https://ncbi.nlm.nih.gov/pubmed/27390654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40064-016-2536-3
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