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Expanding the genetic editing tool kit: ZFNs, TALENs, and CRISPR-Cas9
The past decade has been one of rapid innovation in genome-editing technology. The opportunity now exists for investigators to manipulate virtually any gene in a diverse range of cell types and organisms with targeted nucleases designed with sequence-specific DNA-binding domains. The rapid developme...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4191047/ https://ncbi.nlm.nih.gov/pubmed/25271723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI72992 |
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