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Comparison of CRISPR/Cas9 and TALENs on editing an integrated EGFP gene in the genome of HEK293FT cells

BACKGROUND: Genome editors such as CRISPR/Cas9 and TALENs are at the forefront of research into methodologies for targeted modification of the mammalian genome. To date few comparative studies have been carried out to investigate the difference of genome editing characteristics between CRISPR/Cas9 a...

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Bibliografiske detaljer
Udgivet i:Springerplus
Main Authors: He, Zuyong, Proudfoot, Chris, Whitelaw, C. Bruce A., Lillico, Simon G.
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4916124/
https://ncbi.nlm.nih.gov/pubmed/27390654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40064-016-2536-3
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