Efficient nonmeiotic allele introgression in livestock using custom endonucleases

We have expanded the livestock gene editing toolbox to include transcription activator-like (TAL) effector nuclease (TALEN)- and clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9-stimulated homology-directed repair (HDR) using plasmid, rAAV, and oligonucleotide templates. Towar...

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Main Authors: Tan, Wenfang, Carlson, Daniel F., Lancto, Cheryl A., Garbe, John R., Webster, Dennis A., Hackett, Perry B., Fahrenkrug, Scott C.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2013
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799378/
https://ncbi.nlm.nih.gov/pubmed/24014591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1310478110
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