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Efficient introgression of allelic variants by embryo-mediated editing of the bovine genome

The recent development of designer nucleases allows for the efficient and precise introduction of genetic change into livestock genomes. Most studies so far have focused on the introduction of random mutations in cultured cells and the use of nuclear transfer to generate animals with edited genotype...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Wei, Jingwei, Wagner, Stefan, Lu, Dan, Maclean, Paul, Carlson, Daniel F., Fahrenkrug, Scott C., Laible, Götz
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496724/
https://ncbi.nlm.nih.gov/pubmed/26156133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11735
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