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RAD001 (everolimus) inhibits tumour growth in xenograft models of human hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is the fifth most common malignancy worldwide and highly resistant to available chemotherapies. Mammalian target of rapamycin (mTOR) functions to regulate protein translation, angiogenesis and cell cycle progression in many cancers including HCC. In the present study,...

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Bibliografski detalji
Izdano u:J Cell Mol Med
Glavni autori: Huynh, Hung, Pierce Chow, KH, Soo, Khee Chee, Toh, Han Chong, Choo, Su Pin, Foo, Kian Fong, Poon, Donald, Ngo, Van Chanh, Tran, Evelyn
Format: Artigo
Jezik:Inglês
Izdano: John Wiley & Sons, Ltd 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496150/
https://ncbi.nlm.nih.gov/pubmed/18466352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2008.00364.x
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