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Autophagy controls everolimus (RAD001) activity in mantle cell lymphoma

Mantle cell lymphoma (MCL) is an aggressive neoplasm, which lacks effective therapy. The mechanistic target of rapamycin (MTOR) kinase inhibitor everolimus (RAD001) has shown activity in preclinical and clinical models of MCL, despite the fact that its mechanism of action has not been fully elucidat...

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Autors principals: Rosich, Laia, Colomer, Dolors, Roué, Gaël
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3542214/
https://ncbi.nlm.nih.gov/pubmed/23079699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.22483
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