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Autophagy controls everolimus (RAD001) activity in mantle cell lymphoma

Mantle cell lymphoma (MCL) is an aggressive neoplasm, which lacks effective therapy. The mechanistic target of rapamycin (MTOR) kinase inhibitor everolimus (RAD001) has shown activity in preclinical and clinical models of MCL, despite the fact that its mechanism of action has not been fully elucidat...

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Detalhes bibliográficos
Main Authors: Rosich, Laia, Colomer, Dolors, Roué, Gaël
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3542214/
https://ncbi.nlm.nih.gov/pubmed/23079699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.22483
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