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Autophagy controls everolimus (RAD001) activity in mantle cell lymphoma
Mantle cell lymphoma (MCL) is an aggressive neoplasm, which lacks effective therapy. The mechanistic target of rapamycin (MTOR) kinase inhibitor everolimus (RAD001) has shown activity in preclinical and clinical models of MCL, despite the fact that its mechanism of action has not been fully elucidat...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Landes Bioscience
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3542214/ https://ncbi.nlm.nih.gov/pubmed/23079699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.22483 |
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