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FTY720-induced blockage of autophagy enhances anticancer efficacy of milatuzumab in mantle cell lymphoma: Is FTY720 the next autophagy-blocking agent in lymphoma treatment?
Inhibition of the autophagic pathway has recently revealed promising results in increasing pro-death activity of multiple cancer therapeutics. Here, we discuss our findings regarding the autophagy-blocking and anti-neoplastic effects of a synthetic sphingosine analog, FTY720, in mantle cell lymphoma...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3337842/ https://ncbi.nlm.nih.gov/pubmed/22377620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.19050 |
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