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FTY720-induced blockage of autophagy enhances anticancer efficacy of milatuzumab in mantle cell lymphoma: Is FTY720 the next autophagy-blocking agent in lymphoma treatment?

Inhibition of the autophagic pathway has recently revealed promising results in increasing pro-death activity of multiple cancer therapeutics. Here, we discuss our findings regarding the autophagy-blocking and anti-neoplastic effects of a synthetic sphingosine analog, FTY720, in mantle cell lymphoma...

詳細記述

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書誌詳細
主要な著者: Alinari, Lapo, Baiocchi, Robert A., Prætorius-Ibba, Mette
フォーマット: Artigo
言語:Inglês
出版事項: Landes Bioscience 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337842/
https://ncbi.nlm.nih.gov/pubmed/22377620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.19050
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