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EVEROLIMUS (RAD001) AND THE MTOR PATHWAY IN LOW-GRADE GLIOMAS
BACKGROUND: Low-grade gliomas (LGG) are slow growing, primary brain tumors that frequently recur after primary surgical treatment. Recent work has suggested the activation of the PI3K/mTOR pathway in >50% of LGG, raising the possibility that treatment with mTOR inhibitors such as everolimus (RAD0...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4144638/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou209.24 |
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