LGG-53. PNOC001 (NCT01734512): A PHASE II STUDY OF EVEROLIMUS FOR RECURRENT OR PROGRESSIVE PEDIATRIC LOW-GRADE GLIOMAS (pLGG)

OBJECTIVE: To estimate the 6-month Progression Free Survival (PFS6) associated with everolimus for progressive/recurrent pLGGs and to determine if activated PI3K/Akt/mTOR pathway as measured by positive phosphorylated-ribosomal protein S6 (p-RPS6) status was associated with response. METHOD: Patient...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neuro Oncol
Prif Awduron: Mueller, Sabine, Aboian, Mariam, Nazemi, Kellie, Gauvain, Karen, Yoon, Janet, Minturn, Jane, Leary, Sarah, AbdelBaki, Mohamed S, Goldman, Stewart, Elster, Jennifer, Resnick, Adam, Molinaro, Annette M, Phillips, Joanna, Prados, Michael, Haas-Kogan, Daphne
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2020
Pynciau:
Low Grade Glioma
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715067/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.431
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