RAD001 (everolimus) inhibits tumour growth in xenograft models of human hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is the fifth most common malignancy worldwide and highly resistant to available chemotherapies. Mammalian target of rapamycin (mTOR) functions to regulate protein translation, angiogenesis and cell cycle progression in many cancers including HCC. In the present study,...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Huynh, Hung, Pierce Chow, KH, Soo, Khee Chee, Toh, Han Chong, Choo, Su Pin, Foo, Kian Fong, Poon, Donald, Ngo, Van Chanh, Tran, Evelyn
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496150/
https://ncbi.nlm.nih.gov/pubmed/18466352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2008.00364.x
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