RAD001 (everolimus) inhibits tumour growth in xenograft models of human hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is the fifth most common malignancy worldwide and highly resistant to available chemotherapies. Mammalian target of rapamycin (mTOR) functions to regulate protein translation, angiogenesis and cell cycle progression in many cancers including HCC. In the present study,...

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Publicat a:J Cell Mol Med
Autors principals: Huynh, Hung, Pierce Chow, KH, Soo, Khee Chee, Toh, Han Chong, Choo, Su Pin, Foo, Kian Fong, Poon, Donald, Ngo, Van Chanh, Tran, Evelyn
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons, Ltd 2009
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496150/
https://ncbi.nlm.nih.gov/pubmed/18466352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2008.00364.x
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