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CCN5 attenuates profibrotic phenotypes of fibroblasts through the Smad6-CCN2 pathway: Potential role in epidural fibrosis

Epidural fibrosis is characterized by the development of dense and thick scar tissue adjacent to the dural mater and ranked as the major contributor for post-operative pain recurrence after laminectomy or discectomy. Recently, CCN5 exhibited an inhibitory effect on connective tissue growth factor (C...

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Detalhes bibliográficos
Publicado no:Int J Mol Med
Main Authors: XU, HONGHAI, LIU, CONG, SUN, ZHENGMING, GUO, XIONG, ZHANG, YUELIN, LIU, MENGTING, LI, PENG
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4494601/
https://ncbi.nlm.nih.gov/pubmed/25901787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2015.2190
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