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Mechanical regulation of cardiac fibroblast profibrotic phenotypes

Cardiac fibrosis is a serious condition currently lacking effective treatments. It occurs as a result of cardiac fibroblast (CFB) activation and differentiation into myofibroblasts, characterized by proliferation, extracellular matrix (ECM) production and stiffening, and contraction due to the expre...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Herum, Kate M., Choppe, Jonas, Kumar, Aditya, Engler, Adam J., McCulloch, Andrew D.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5541838/
https://ncbi.nlm.nih.gov/pubmed/28468977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-01-0014
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