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Mechanical regulation of cardiac fibroblast profibrotic phenotypes

Cardiac fibrosis is a serious condition currently lacking effective treatments. It occurs as a result of cardiac fibroblast (CFB) activation and differentiation into myofibroblasts, characterized by proliferation, extracellular matrix (ECM) production and stiffening, and contraction due to the expre...

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Bibliografiska uppgifter
I publikationen:Mol Biol Cell
Huvudupphovsmän: Herum, Kate M., Choppe, Jonas, Kumar, Aditya, Engler, Adam J., McCulloch, Andrew D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Cell Biology 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5541838/
https://ncbi.nlm.nih.gov/pubmed/28468977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-01-0014
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