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Mechanical regulation of gene expression in cardiac myocytes and fibroblasts

The intact heart undergoes complex and multiscale remodelling processes in response to altered mechanical cues. Remodelling of the myocardium is regulated by a combination of myocyte and non-myocyte responses to mechanosensitive pathways, which can alter gene expression and therefore function in the...

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Detalhes bibliográficos
Publicado no:Nat Rev Cardiol
Main Authors: Saucerman, Jeffrey J., Tan, Philip M., Buchholz, Kyle S., McCulloch, Andrew D., Omens, Jeffrey H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6525041/
https://ncbi.nlm.nih.gov/pubmed/30683889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41569-019-0155-8
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