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Mechanical regulation of gene expression in cardiac myocytes and fibroblasts

The intact heart undergoes complex and multiscale remodelling processes in response to altered mechanical cues. Remodelling of the myocardium is regulated by a combination of myocyte and non-myocyte responses to mechanosensitive pathways, which can alter gene expression and therefore function in the...

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Detalles Bibliográficos
Publicado en:Nat Rev Cardiol
Autores principales: Saucerman, Jeffrey J., Tan, Philip M., Buchholz, Kyle S., McCulloch, Andrew D., Omens, Jeffrey H.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6525041/
https://ncbi.nlm.nih.gov/pubmed/30683889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41569-019-0155-8
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