TAZ contributes to pulmonary fibrosis by activating profibrotic functions of lung fibroblasts

Transcriptional coactivator with PDZ-binding motif (TAZ) regulates a variety of biological processes. Nuclear translocation and activation of TAZ are regulated by multiple mechanisms, including actin cytoskeleton and mechanical forces. TAZ is involved in lung alveolarization during lung development...

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Publicado no:Sci Rep
Main Authors: Noguchi, Satoshi, Saito, Akira, Mikami, Yu, Urushiyama, Hirokazu, Horie, Masafumi, Matsuzaki, Hirotaka, Takeshima, Hideyuki, Makita, Kosuke, Miyashita, Naoya, Mitani, Akihisa, Jo, Taisuke, Yamauchi, Yasuhiro, Terasaki, Yasuhiro, Nagase, Takahide
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5307361/
https://ncbi.nlm.nih.gov/pubmed/28195168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42595
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