PPAR-γ agonists inhibit profibrotic phenotypes in human lung fibroblasts and bleomycin-induced pulmonary fibrosis

Pulmonary fibrosis is characterized by alterations in fibroblast phenotypes resulting in excessive extracellular matrix accumulation and anatomic remodeling. Current therapies for this condition are largely ineffective. Peroxisome proliferator-activated receptor-γ (PPAR-γ) is a member of the nuclear...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Milam, Jami E., Keshamouni, Venkateshwar G., Phan, Sem H., Hu, Biao, Gangireddy, Srinivasa R., Hogaboam, Cory M., Standiford, Theodore J., Thannickal, Victor J., Reddy, Raju C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926773/
https://ncbi.nlm.nih.gov/pubmed/18162602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00333.2007
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados