Chemotherapeutic Drugs Induce PPAR-γ Expression and Show Sequence-Specific Synergy with PPAR-γ Ligands in Inhibition of Non-Small Cell Lung Cancer

Preclinical studies have shown that peroxisome proliferator-activated receptor γ (PPAR-γ) ligands can exert antitumor effects against non-small cell lung cancer (NSCLC) and a variety of other cancers. In this study, we investigate the potential use of a PPAR-γ ligand, troglitazone (Tro), in combinat...

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Detalhes bibliográficos
Main Authors: Reddy, Raju C, Srirangam, Anjaiah, Reddy, Kaunteya, Chen, Jun, Gangireddy, Srinivasareddy, Kalemkerian, Gregory P, Standiford, Theodore J, Keshamouni, Venkateshwar G
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386544/
https://ncbi.nlm.nih.gov/pubmed/18516296
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