Sepsis-induced inhibition of neutrophil chemotaxis is mediated by activation of peroxisome proliferator-activated receptor-γ

Neutrophils (polymorphonuclear leukocytes [PMNs]) are critical to the immune response, including clearance of infectious pathogens. Sepsis is associated with impaired PMN function, including chemotaxis. PMNs express peroxisome proliferator-activated receptor-γ (PPAR-γ), a ligand-activated nuclear tr...

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Dades bibliogràfiques
Autors principals: Reddy, Raju C., Narala, Venkata R., Keshamouni, Venkateshwar G., Milam, Jami E., Newstead, Michael W., Standiford, Theodore J.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2008
Matèries:
Phagocytes
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582007/
https://ncbi.nlm.nih.gov/pubmed/18535203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-12-128967
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