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Multi-format T-cell Engaging Bispecific Antibodies Targeting Human: Breast Cancers
We generated four different formats of bispecific antibodies (bsAbs) consisting of anti-Her2 IgG or Fab site-specifically conjugated to anti-CD3 Fab using the genetically encoded noncanonical amino acid. These bsAbs varied in valency, or in the presence or absence of an Fc domain. Different valencie...
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Publicado no: | Angew Chem Int Ed Engl |
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Main Authors: | , , , , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4492699/ https://ncbi.nlm.nih.gov/pubmed/25919418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201500799 |
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