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Role of tRNA Orthogonality in an Expanded Genetic Code
[Image: see text] We found that Methanocaldococcus jannaschii DSM2661 tyrosyl-tRNA synthetase (Mj E9RS), specifically evolved to charge its cognate tRNA with the unnatural amino acid p-acetylphenylalanine (pAcF) in E. coli, misaminoacylates the endogenous E. coli prolyl-tRNAs with pAcF at a low leve...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American
Chemical
Society
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4167058/ https://ncbi.nlm.nih.gov/pubmed/24443971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb4005172 |
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