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Aminoacyl-tRNA Synthetases and tRNAs for an Expanded Genetic Code: What Makes them Orthogonal?

In the past two decades, tRNA molecules and their corresponding aminoacyl-tRNA synthetases (aaRS) have been extensively used in synthetic biology to genetically encode post-translationally modified and unnatural amino acids. In this review, we briefly examine one fundamental requirement for the succ...

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Detalhes bibliográficos
Main Authors: Sergey V. Melnikov, Dieter Söll
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2019-04-01
Colecção:International Journal of Molecular Sciences
Assuntos:
Acesso em linha:https://www.mdpi.com/1422-0067/20/8/1929
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