Oncogenic Role of miR-15a-3p in 13q Amplicon-Driven Colorectal Adenoma-to-Carcinoma Progression

Progression from colorectal adenoma to carcinoma is strongly associated with an accumulation of genomic alterations, including gain of chromosome 13. This gain affects the whole q arm and is present in 40%–60% of all colorectal cancers (CRCs). Several genes located at this amplicon are known to be o...

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Sparad:
Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: de Groen, Florence L. M., Timmer, Lisette M., Menezes, Renee X., Diosdado, Begona, Hooijberg, Erik, Meijer, Gerrit A., Steenbergen, Renske D. M., Carvalho, Beatriz
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2015
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492490/
https://ncbi.nlm.nih.gov/pubmed/26148070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0132495
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