Promoter methylation of Wnt-antagonists in polypoid and nonpolypoid colorectal adenomas

BACKGROUND: Nonpolypoid adenomas are a subgroup of colorectal adenomas that have been associated with a more aggressive clinical behaviour compared to their polypoid counterparts. A substantial proportion of nonpolypoid and polypoid adenomas lack APC mutations, APC methylation or chromosomal loss of...

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Detalhes bibliográficos
Main Authors: Voorham, Quirinus JM, Janssen, Jerry, Tijssen, Marianne, Snellenberg, Suzanne, Mongera, Sandra, van Grieken, Nicole CT, Grabsch, Heike, Kliment, Martin, Rembacken, Bjorn J, Mulder, Chris JJ, van Engeland, Manon, Meijer, Gerrit A, Steenbergen, Renske DM, Carvalho, Beatriz
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3878219/
https://ncbi.nlm.nih.gov/pubmed/24350795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-603
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