MiR-17-92 cluster is associated with 13q gain and c-myc expression during colorectal adenoma to adenocarcinoma progression

BACKGROUND: MicroRNAs are small non-coding RNA molecules, which regulate central mechanisms of tumorigenesis. In colorectal tumours, the combination of gain of 8q and 13q is one of the major factors associated with colorectal adenoma to adenocarcinoma progression. Functional studies on the miR-17-92...

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Detalhes bibliográficos
Main Authors: Diosdado, B, van de Wiel, M A, Terhaar Sive Droste, J S, Mongera, S, Postma, C, Meijerink, W J H J, Carvalho, B, Meijer, G A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Genetics and Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736819/
https://ncbi.nlm.nih.gov/pubmed/19672269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605037
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