Colorectal adenoma to carcinoma progression is accompanied by changes in gene expression associated with ageing, chromosomal instability, and fatty acid metabolism

BACKGROUND: Colorectal cancer develops in a multi-step manner from normal epithelium, through a pre-malignant lesion (so-called adenoma), into a malignant lesion (carcinoma), which invades surrounding tissues and eventually can spread systemically (metastasis). It is estimated that only about 5% of...

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Detalhes bibliográficos
Main Authors: Carvalho, Beatriz, Sillars-Hardebol, Anke H., Postma, Cindy, Mongera, Sandra, Droste, Jochim Terhaar Sive, Obulkasim, Askar, van de Wiel, Mark, van Criekinge, Wim, Ylstra, Bauke, Fijneman, Remond J. A., Meijer, Gerrit A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2012
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308003/
https://ncbi.nlm.nih.gov/pubmed/22278361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13402-011-0065-1
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