Methylation-mediated silencing and tumour suppressive function of hsa-miR-124 in cervical cancer

BACKGROUND: A substantial number of microRNAs (miRNAs) is subject to epigenetic silencing in cancer. Although epigenetic silencing of tumour suppressor genes is an important feature of cervical cancer, little is known about epigenetic silencing of miRNAs. Since DNA methylation-based silencing of hsa...

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Hauptverfasser: Wilting, Saskia M, van Boerdonk, Robert AA, Henken, Florianne E, Meijer, Chris JLM, Diosdado, Begoňa, Meijer, Gerrit A, le Sage, Carlos, Agami, Reuven, Snijders, Peter JF, Steenbergen, Renske DM
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2010
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917428/
https://ncbi.nlm.nih.gov/pubmed/20579385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-167
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