Methylation-mediated silencing and tumour suppressive function of hsa-miR-124 in cervical cancer

BACKGROUND: A substantial number of microRNAs (miRNAs) is subject to epigenetic silencing in cancer. Although epigenetic silencing of tumour suppressor genes is an important feature of cervical cancer, little is known about epigenetic silencing of miRNAs. Since DNA methylation-based silencing of hsa...

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Detalhes bibliográficos
Main Authors: Wilting, Saskia M, van Boerdonk, Robert AA, Henken, Florianne E, Meijer, Chris JLM, Diosdado, Begoňa, Meijer, Gerrit A, le Sage, Carlos, Agami, Reuven, Snijders, Peter JF, Steenbergen, Renske DM
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917428/
https://ncbi.nlm.nih.gov/pubmed/20579385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-167
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