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Methylation-mediated transcriptional repression of microRNAs during cervical carcinogenesis

Deregulated expression of microRNAs (miRNAs) is common and biologically relevant in cervical carcinogenesis and appears only partly related to chromosomal changes. We recently identified 32 miRNAs showing decreased expression in high-grade cervical intraepithelial neoplasia (CIN) and carcinomas not...

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Detalles Bibliográficos
Main Authors: Wilting, Saskia M., Verlaat, Wina, Jaspers, Annelieke, Makazaji, Nour A., Agami, Reuven, Meijer, Chris J.L.M., Snijders, Peter J.F., Steenbergen, Renske D.M.
Formato: Artigo
Idioma:Inglês
Publicado: Landes Bioscience 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592908/
https://ncbi.nlm.nih.gov/pubmed/23324622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.23605
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