Methylation-mediated transcriptional repression of microRNAs during cervical carcinogenesis

Deregulated expression of microRNAs (miRNAs) is common and biologically relevant in cervical carcinogenesis and appears only partly related to chromosomal changes. We recently identified 32 miRNAs showing decreased expression in high-grade cervical intraepithelial neoplasia (CIN) and carcinomas not...

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Главные авторы: Wilting, Saskia M., Verlaat, Wina, Jaspers, Annelieke, Makazaji, Nour A., Agami, Reuven, Meijer, Chris J.L.M., Snijders, Peter J.F., Steenbergen, Renske D.M.
Формат: Artigo
Язык:Inglês
Опубликовано: Landes Bioscience 2013
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Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592908/
https://ncbi.nlm.nih.gov/pubmed/23324622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.23605
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