PIK3CA-mediated PI3-kinase signalling is essential for HPV-induced transformation in vitro

BACKGROUND: High-risk human papillomavirus (hrHPV) infections are causally related to cervical cancer development. The additional (epi)genetic alterations driving malignant transformation of hrHPV-infected cells however, are not yet fully elucidated. In this study we experimentally assessed the role...

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Detalhes bibliográficos
Main Authors: Henken, Florianne E, Banerjee, N Sanjib, Snijders, Peter JF, Meijer, Chris JLM, De-Castro Arce, Johanna, Rösl, Frank, Broker, Thomas R, Chow, Louise T, Steenbergen, Renske DM
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130697/
https://ncbi.nlm.nih.gov/pubmed/21663621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-10-71
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