hTERT promoter activity and CpG methylation in HPV-induced carcinogenesis

BACKGROUND: Activation of telomerase resulting from deregulated hTERT expression is a key event during high-risk human papillomavirus (hrHPV)-induced cervical carcinogenesis. In the present study we examined hTERT promoter activity and its relation to DNA methylation as one of the potential mechanis...

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Hauptverfasser: de Wilde, Jillian, Kooter, Jan M, Overmeer, Renée M, Claassen-Kramer, Debbie, Meijer, Chris JLM, Snijders, Peter JF, Steenbergen, Renske DM
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2010
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904279/
https://ncbi.nlm.nih.gov/pubmed/20534141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-271
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