STAT4 controls GM-CSF production by both Th1 and Th17 cells during EAE

BACKGROUND: In experimental autoimmune encephalomyelitis (EAE), a mouse model of multiple sclerosis, mice genetically deficient in the transcription factor signal transducer and activator of transcription 4 (STAT4) are resistant to disease. In contrast, deletion or inhibition of the Th1-associated c...

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Bibliographic Details
Published in:J Neuroinflammation
Main Authors: McWilliams, Ian L., Rajbhandari, Rajani, Nozell, Susan, Benveniste, Etty, Harrington, Laurie E.
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491892/
https://ncbi.nlm.nih.gov/pubmed/26123499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0351-3
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