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STAT4 controls GM-CSF production by both Th1 and Th17 cells during EAE
BACKGROUND: In experimental autoimmune encephalomyelitis (EAE), a mouse model of multiple sclerosis, mice genetically deficient in the transcription factor signal transducer and activator of transcription 4 (STAT4) are resistant to disease. In contrast, deletion or inhibition of the Th1-associated c...
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| Publicado no: | J Neuroinflammation |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4491892/ https://ncbi.nlm.nih.gov/pubmed/26123499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0351-3 |
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