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IFNγ inhibits Th17 differentiation and function via Tbet-dependent and Tbet-independent mechanisms
The transcription factor Tbet is critical for the differentiation of Th1 CD4 T cells and is associated with the induction of multiple autoimmune diseases, including experimental autoimmune encephalomyelitis (EAE). Herein, we demonstrate that Tbet suppresses IL-17A and Th17 differentiation both in vi...
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| Publicado no: | J Neuroimmunol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4363997/ https://ncbi.nlm.nih.gov/pubmed/24369297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2013.12.001 |
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