Pathogenicity of IFN-γ–producing Th17 cells is independent of T-bet

During the development of experimental autoimmune encephalomyelitis (EAE), the proportion of pathogenic and myelin-specific cells within CNS-infiltrating cytokine producing T helper (Th) cells is unknown. Using an IL-17A-IFN-γ double reporter mouse and I-A(b)/MOG(38–49) tetramer, we show here that I...

Full description

Saved in:
Bibliographic Details
Main Authors: Duhen, Rebekka, Glatigny, Simon, Arbelaez, Carlos A., Blair, Tiffany C., Oukka, Mohamed, Bettelli, Estelle
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633668/
https://ncbi.nlm.nih.gov/pubmed/23543757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1203172
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items