IL-7/IL-7R signaling differentially affects effector CD4(+) T cell subsets involved in experimental autoimmune encephalomyelitis

IL-17-producing CD4(+) T (Th17) cells, along with IFN-gamma-expressing Th1 cells, represent two major pathogenic T cell subsets in experimental autoimmune encephalomyelitis (EAE), the animal model of multiple sclerosis (MS). The cytokines and transcription factors involved in the development and eff...

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Vydáno v:J Immunol
Hlavní autoři: Arbelaez, Carlos A, Glatigny, Simon, Duhen, Rebekka, Eberl, Gerard, Oukka, Mohamed, Bettelli, Estelle
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546887/
https://ncbi.nlm.nih.gov/pubmed/26223651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1403135
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