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IL-7/IL-7R signaling differentially affects effector CD4(+) T cell subsets involved in experimental autoimmune encephalomyelitis
IL-17-producing CD4(+) T (Th17) cells, along with IFN-gamma-expressing Th1 cells, represent two major pathogenic T cell subsets in experimental autoimmune encephalomyelitis (EAE), the animal model of multiple sclerosis (MS). The cytokines and transcription factors involved in the development and eff...
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| Publicado no: | J Immunol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4546887/ https://ncbi.nlm.nih.gov/pubmed/26223651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1403135 |
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