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Loss of alpha4 integrin expression differentially affects the homing of Th1 and Th17 cells

The neutralization of alpha 4 integrin is currently used as treatment in several autoimmune diseases and is thought to prevent the entry of most immune cells in target tissues. Here, we showed that selective deletion of alpha4 integrin in T cells did not prevent but delayed the development of experi...

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Detalhes bibliográficos
Main Authors: Glatigny, Simon, Duhen, Rebekka, Oukka, Mohamed, Bettelli, Estelle
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237912/
https://ncbi.nlm.nih.gov/pubmed/22084440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102515
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