Nrf2 reduces allergic asthma in mice through enhanced airway epithelial cytoprotective function

Asthma development and pathogenesis are influenced by the interactions of airway epithelial cells and innate and adaptive immune cells in response to allergens. Oxidative stress is an important mediator of asthmatic phenotypes in these cell types. Nuclear erythroid 2-related factor 2 (Nrf2) is a red...

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Published in:Am J Physiol Lung Cell Mol Physiol
Main Authors: Sussan, Thomas E., Gajghate, Sachin, Chatterjee, Samit, Mandke, Pooja, McCormick, Sarah, Sudini, Kuladeep, Kumar, Sarvesh, Breysse, Patrick N., Diette, Gregory B., Sidhaye, Venkataramana K., Biswal, Shyam
Format: Artigo
Language:Inglês
Published: American Physiological Society 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491510/
https://ncbi.nlm.nih.gov/pubmed/25957295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00398.2014
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